Kerber R E, Kouba C, Martins J, Kelly K, Low R, Hoyt R, Ferguson D, Bailey L, Bennett P, Charbonnier F
Circulation. 1984 Aug;70(2):303-8. doi: 10.1161/01.cir.70.2.303.
The purposes of this study were to evaluate a method that predicts transthoracic impedance in advance of defibrillating shocks in humans and to assess the importance of transthoracic impedance in low-energy defibrillation. Via defibrillator electrodes we applied 31 kHz current to the chest during the defibrillator charge cycle, before the defibrillating shock was actually delivered. The current flow was limited by transthoracic impedance; a microprocessor monitored the predischarge current flow and determined the predischarge impedance by calibration against known resistance values. Actual impedance to the defibrillating shock was also determined and compared with the predicted impedance. With this approach we predicted impedance in 19 patients who received 66 shocks for ventricular and atrial arrhythmias. Predicted impedance (y) correlated very well with actual impedance (x):y = .90x + 11.3; r = .97. To determine the importance of impedance in defibrillation and cardioversion, we prospectively gathered data from 96 patients who received shocks of various energies for ventricular or atrial arrhythmias. In patients with high transthoracic impedance (greater than 97 omega), low-energy shocks (less than or equal to 100 J) for ventricular defibrillation had only a 20% success rate as opposed to a 70% success rate for low-energy shocks in patients with low or average impedance (p less than .05). We conclude that transthoracic impedance can be accurately predicted in advance of defibrillation and cardioversion. This method permits the preshock identification of patients with high impedance in whom attempts to defibrillate with low-energy shocks are inappropriate.
本研究的目的是评估一种在人类除颤电击前预测经胸阻抗的方法,并评估经胸阻抗在低能量除颤中的重要性。在除颤电击实际发放之前,通过除颤器电极在除颤器充电周期内向胸部施加31kHz电流。电流流动受经胸阻抗限制;微处理器监测预放电电流流动,并通过与已知电阻值校准来确定预放电阻抗。还确定了对除颤电击的实际阻抗,并与预测阻抗进行比较。采用这种方法,我们对19例因室性和房性心律失常接受66次电击的患者进行了阻抗预测。预测阻抗(y)与实际阻抗(x)相关性非常好:y = 0.90x + 11.3;r = 0.97。为了确定阻抗在除颤和心脏复律中的重要性,我们前瞻性收集了96例因室性或房性心律失常接受不同能量电击的患者的数据。在经胸阻抗高(大于97Ω)的患者中,用于室性除颤的低能量电击(小于或等于100J)成功率仅为20%,而在低阻抗或平均阻抗患者中低能量电击的成功率为70%(p < 0.05)。我们得出结论,在除颤和心脏复律前可以准确预测经胸阻抗。这种方法允许在电击前识别出高阻抗患者,对于这些患者,尝试用低能量电击除颤是不合适的。