多效超显性与多基因性状遗传变异的维持
Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters.
作者信息
Gillespie J H
出版信息
Genetics. 1984 Jun;107(2):321-30. doi: 10.1093/genetics/107.2.321.
Abstract
A model of selection is described in which optimizing phenotypic selection is combined with pleiotropic overdominance. Thus, the role that mutation commonly plays in models of phenotypic evolution is replaced by balancing selection. Expressions are provided for the equilibrium genetic variance in phenotype and for the heterozygosity. An approximate analysis of the transient properties of the model shows that, in certain circumstances, the behavior is quite similar to that of models based on the interaction of mutation and selection.
摘要
描述了一种选择模型，其中优化表型选择与多效超显性相结合。因此，突变在表型进化模型中通常所起的作用被平衡选择所取代。给出了表型平衡遗传方差和杂合性的表达式。对该模型瞬态特性的近似分析表明，在某些情况下，其行为与基于突变和选择相互作用的模型非常相似。
相似文献
1
Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters.多效超显性与多基因性状遗传变异的维持
Genetics. 1984 Jun;107(2):321-30. doi: 10.1093/genetics/107.2.321.
2
Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits.多效性对多基因性状突变-选择平衡预测的影响。
Genetics. 1985 Sep;111(1):165-95. doi: 10.1093/genetics/111.1.165.
3
Pleiotropic models of polygenic variation, stabilizing selection, and epistasis.多基因变异、稳定选择和上位性的多效性模型。
Genetics. 1993 Jun;134(2):609-25. doi: 10.1093/genetics/134.2.609.
4
Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters.在稳定选择下维持的加性变异：两个数量性状的多效性双位点模型。
Genetics. 1986 Mar;112(3):717-25. doi: 10.1093/genetics/112.3.717.
5
Biochemical heterozygosity and phenotypic variability of polygenic traits.多基因性状的生化杂合性与表型变异性。
Heredity (Edinb). 1987 Aug;59 ( Pt 1):19-28. doi: 10.1038/hdy.1987.92.
6
[Dominant monogenic markers of quantitative characters].[数量性状的显性单基因标记]
Genetika. 1995 Oct;31(10):1438-44.
7
Differential dominance of pleiotropic loci for mouse skeletal traits.小鼠骨骼性状多效性位点的差异显性
Evolution. 2009 Jul;63(7):1845-51. doi: 10.1111/j.1558-5646.2009.00681.x. Epub 2009 Apr 19.
8
The selection limit due to the conflict between truncation and stabilizing selection with mutation.由于截断选择与稳定选择和突变之间的冲突导致的选择极限。
Genetics. 1986 Dec;114(4):1313-28. doi: 10.1093/genetics/114.4.1313.
9
The selective value of alleles underlying polygenic traits.多基因性状相关等位基因的选择价值。
Genetics. 1984 Dec;108(4):1021-33. doi: 10.1093/genetics/108.4.1021.
10
Maintenance of polygenic variation through mutation-selection balance: bifurcation analysis of a biallelic model.通过突变-选择平衡维持多基因变异：双等位基因模型的分岔分析
J Math Biol. 1990;28(3):329-40. doi: 10.1007/BF00178781.
引用本文的文献
1
Maintenance of Complex Trait Variation: Classic Theory and Modern Data.复杂性状变异的维持：经典理论与现代数据
Front Genet. 2021 Nov 12;12:763363. doi: 10.3389/fgene.2021.763363. eCollection 2021.
2
Genotype-environment interaction and the maintenance of genetic variation: an empirical study of (Campanulaceae).基因型-环境互作与遗传变异的维持：对风铃草属（桔梗科）的一项实证研究
R Soc Open Sci. 2020 Mar 18;7(3):191720. doi: 10.1098/rsos.191720. eCollection 2020 Mar.
3
Rapid sex-specific adaptation to high temperature in .在 中，性别特异性对高温的快速适应。
Elife. 2020 Feb 21;9:e53237. doi: 10.7554/eLife.53237.
4
Rapid evolution of prey maintains predator diversity.猎物的快速进化维持了捕食者的多样性。
PLoS One. 2019 Dec 31;14(12):e0227111. doi: 10.1371/journal.pone.0227111. eCollection 2019.
5
Extreme copy number variation at a tRNA ligase gene affecting phenology and fitness in yellow monkeyflowers.tRNA 连接酶基因的极端拷贝数变异影响黄蔓花的物候和适应性。
Mol Ecol. 2019 Mar;28(6):1460-1475. doi: 10.1111/mec.14904. Epub 2018 Dec 10.
6
Selective sweeps in multilocus models of quantitative traits.选择清除在数量性状的多点模型中。
Genetics. 2012 Sep;192(1):225-39. doi: 10.1534/genetics.112.142547. Epub 2012 Jun 19.
7
Experimental evolution of resistance against a competing fungus in Drosophila melanogaster.在黑腹果蝇中对竞争真菌的抗性的实验进化。
Oecologia. 2009 Oct;161(4):781-90. doi: 10.1007/s00442-009-1414-x. Epub 2009 Jul 14.
8
Genotype-environment interactions and the maintenance of polygenic variation.基因型-环境互作与多基因变异的维持。
Genetics. 1989 Jan;121(1):129-38. doi: 10.1093/genetics/121.1.129.
9
Regional heterogeneity and gene flow maintain variance in a quantitative trait within populations of lodgepole pine.区域异质性和基因流维持了黑松种群内数量性状的变异。
Proc Biol Sci. 2006 Jul 7;273(1594):1587-93. doi: 10.1098/rspb.2006.3498.
10
Theoretical models of selection and mutation on quantitative traits.数量性状的选择与突变理论模型。
Philos Trans R Soc Lond B Biol Sci. 2005 Jul 29;360(1459):1411-25. doi: 10.1098/rstb.2005.1667.
本文引用的文献
1
The genetic variability of polygenic characters under optimizing selection, mutation and drift.在优化选择、突变和漂变作用下多基因性状的遗传变异性。
Genet Res. 1972 Feb;19(1):17-25. doi: 10.1017/s0016672300014221.
2
Heterosis or neutrality?杂种优势还是中性？
Genetics. 1977 Apr;85(4):789-814. doi: 10.1093/genetics/85.4.789.
Zotero 插件