Lacaine F, Huguier M, Gremy F
Nouv Presse Med. 1978 Apr 29;7(17):1451-3.
It is desirable to assess the value of special investigations by objective criteria. Conditional probabilities are suitable for this purpose. Sensitivity and specificity indicate the prevalence of a sign in a disease. Predictive values estimate the probability of a disease when a sign is present and the probability of absence of disease when the sign is absent. Comparison between the informational value of a sign or examination with concepts of cost or of risk to the patient is then possible. This made be used as a basis for determining a strategy for special investigations in the establishment of a diagnosis.
通过客观标准评估特殊检查的价值是可取的。条件概率适用于此目的。敏感性和特异性表明某种体征在疾病中的流行程度。预测值估计当出现某种体征时患疾病的概率以及当该体征不存在时无疾病的概率。然后就可以将某种体征或检查的信息价值与成本概念或对患者的风险进行比较。这可作为确定特殊检查策略以建立诊断的基础。