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4-氯联苯(一种氯化联苯的模型化合物)的微生物降解

Microbial biodegradation of 4-chlorobiphenyl, a model compound of chlorinated biphenyls.

作者信息

Massé R, Messier F, Péloquin L, Ayotte C, Sylvestre M

出版信息

Appl Environ Microbiol. 1984 May;47(5):947-51. doi: 10.1128/aem.47.5.947-951.1984.

DOI:10.1128/aem.47.5.947-951.1984
PMID:6742836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC240022/
Abstract

The biodegradation products of 4-chlorobiphenyl were analyzed in an Achromobacter sp. strain and a Bacillus brevis strain. Both strains generated the same metabolites, with 4-chlorobenzoic acid as the major metabolic product. Our results corroborate previous observations whereby most bacterial strains degrade the chlorobiphenyls via a major pathway which proceeds by an hydroxylation in position 2,3 and a meta-1,2 fission. However, we also detected several metabolites whose structure suggests the existence of other routes for the degradation of chlorinated biphenyls.

摘要

在无色杆菌属菌株和短短芽孢杆菌菌株中分析了4-氯联苯的生物降解产物。两种菌株产生相同的代谢产物,其中4-氯苯甲酸是主要的代谢产物。我们的结果证实了先前的观察结果,即大多数细菌菌株通过在2,3位羟基化和间位1,2裂变的主要途径降解氯联苯。然而,我们也检测到几种代谢产物,其结构表明存在其他降解氯代联苯的途径。

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本文引用的文献

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Bacterial nitration of 4-chlorobiphenyl.细菌对 4-氯联苯的硝化作用。
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Effect of chlorine substitution on the biodegradability of polychlorinated biphenyls.氯取代对多氯联苯生物降解性的影响。
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