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乙撑硫脲：两组暴露工人的甲状腺功能

Ethylene thiourea: thyroid function in two groups of exposed workers.

作者信息

Smith D M

出版信息

Br J Ind Med. 1984 Aug;41(3):362-6. doi: 10.1136/oem.41.3.362.

DOI:10.1136/oem.41.3.362
PMID:6743584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1069358/
Abstract

Ethylene thiourea is manufactured at one factory in the United Kingdom and is mixed into masterbatch rubber at another. Clinical examinations and thyroid function tests were carried out over a period of three years on eight process workers and five mixers and on matched controls. The results show that the exposed mixers, but not exposed process workers, have significantly lower levels of total thyroxine (T4) than the controls. One mixer had an appreciably raised level of thyroid stimulation hormone (TSH).

摘要

乙撑硫脲在英国的一家工厂生产，然后在另一家工厂被混入母炼胶中。对8名生产工人、5名混合工人以及相匹配的对照组进行了为期三年的临床检查和甲状腺功能测试。结果显示，接触过的混合工人，而非接触过的生产工人，其总甲状腺素（T4）水平显著低于对照组。一名混合工人的促甲状腺激素（TSH）水平明显升高。

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本文引用的文献

1
Bioassay of pesticides and industrial chemicals for tumorigenicity in mice: a preliminary note.用于小鼠致癌性的农药和工业化学品生物测定：初步报告。
J Natl Cancer Inst. 1969 Jun;42(6):1101-14.
2
Thyroid cancer in rats from ethylene thiourea intake.
J Natl Cancer Inst. 1972 Aug;49(2):583-4.