叠氮化碘试验与二硫化碳暴露的TTCA试验之间的关系。
Relation between the iodine azide test and the TTCA test for exposure to carbon disulphide.
作者信息
Rosier J, Billemont G, Van Peteghem C, Vanhoorne M, Grosjean R, Van de Walle A
出版信息
Br J Ind Med. 1984 Aug;41(3):412-6. doi: 10.1136/oem.41.3.412.
Exposure to carbon disulphide (CS2) in a viscose plant was measured by personal monitoring and by application of the iodine azide test and quantification of 2-thio-thiazolidine-4-carboxylic-acid (TTCA) in urine samples. A relation was found between the rise in urinary TTCA concentration during the workshift and the exposure index E1. The correlation (r) between the exposure index and the atmospheric concentrations of CS2 in workroom air below 100 mg CS2/m3 was 0.59 (n = 9). The correlation between the increase in TTCA concentrations during the workshift and the atmospheric CS2 concentrations was found to be higher when urine samples at the end of the workshift with creatinine concentrations below 1 mg/ml and above 3 mg/ml were disregarded (from r = 0.61; n = 20 to r = 0.84; n = 14). A high correlation was found (r = 0.86; n = 13) when the end of workshift urine samples were analysed, provided that their creatinine concentrations are not beyond the limits given above.
通过个人监测、叠氮化碘试验以及对尿样中2-硫代噻唑烷-4-羧酸（TTCA）进行定量分析，对粘胶纤维厂中硫化碳（CS2）的接触情况进行了测定。发现工作班次期间尿中TTCA浓度的升高与接触指数E1之间存在关联。当车间空气中CS2浓度低于100 mg CS2/m3时，接触指数与大气中CS2浓度之间的相关性（r）为0.59（n = 9）。当不考虑工作班次结束时肌酐浓度低于1 mg/ml和高于3 mg/ml的尿样时，发现工作班次期间TTCA浓度的升高与大气中CS2浓度之间的相关性更高（从r = 0.61；n = 20提高到r = 0.84；n = 14）。如果分析工作班次结束时的尿样，且其肌酐浓度未超出上述限值，则会发现高度相关性（r = 0.86；n = 13）。
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