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尿中2-硫代噻唑烷-4-羧酸（TTCA）水平作为二硫化碳暴露检测指标的初步评估。

Preliminary evaluation of urinary 2-thio-thiazolidine-4-carboxylic-acid (TTCA) levels as a test for exposure to carbon disulfide.

作者信息

Rosier J, Vanhoorne M, Grosjean R, Van de Walle E, Billemont G, Van Peteghem C

出版信息

Int Arch Occup Environ Health. 1982;51(2):159-67. doi: 10.1007/BF00378160.

DOI:10.1007/BF00378160
PMID:7160915
Abstract

The exposure to carbon disulfide of workers in charge of different jobs in a Belgian viscose plant was measured by means of personal monitoring of the inhaled air and by quantitative assay of 2-thio-thiazolidine-4-carboxylic acid (TTCA) in urine. It was found that the atmospheric carbon disulfide concentration varied considerably among different jobs, among different individuals doing the same jobs and for the same individuals in the course of the working period. The 2-thio-thiazolidine-4-carboxylic-acid levels increased markedly during the exposure. The correlation between individual personal monitoring results and the increase TTCA levels was found to be statistically significant.

摘要

通过对吸入空气进行个人监测以及对尿液中的2-硫代噻唑烷-4-羧酸（TTCA）进行定量分析，测量了比利时一家粘胶工厂中从事不同工作的工人接触二硫化碳的情况。结果发现，不同工作之间、从事相同工作的不同个体之间以及同一工作个体在工作期间，大气中二硫化碳浓度差异很大。暴露期间，2-硫代噻唑烷-4-羧酸水平显著升高。个人监测结果与TTCA水平升高之间的相关性具有统计学意义。

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1
Preliminary evaluation of urinary 2-thio-thiazolidine-4-carboxylic-acid (TTCA) levels as a test for exposure to carbon disulfide.尿中2-硫代噻唑烷-4-羧酸（TTCA）水平作为二硫化碳暴露检测指标的初步评估。
Int Arch Occup Environ Health. 1982;51(2):159-67. doi: 10.1007/BF00378160.
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Carbon disulphide. I. External and internal exposure to carbon disulphide of workers in the viscose industry.二硫化碳。一、粘胶工业工人的二硫化碳内外部暴露情况

本文引用的文献

1
Identification and determination of 2-thiothiazolidine-4-carboxylic acid in urine of workers exposed to carbon disulfide.
Arch Toxicol. 1981 Mar;47(1):51-8. doi: 10.1007/BF00297130.
2
Eight-year follow-up of viscose rayon workers exposed to carbon disulfide.
Scand J Work Environ Health. 1976 Mar;2(1):27-30. doi: 10.5271/sjweh.2824.
3
Biological monitoring. Guest lecture given at the 26th Nordic symposium on industrial hygiene, Helsinki, October 1977.生物监测。1977年10月于赫尔辛基举行的第26届北欧工业卫生研讨会上的客座演讲。
Scand J Work Environ Health. 1978 Mar;4(1):1-18.
Int Arch Occup Environ Health. 1994;65(6):359-65. doi: 10.1007/BF00383244.
4
Carbon disulphide. II. Investigations on the uptake of CS2 and the excretion of its metabolite 2-thiothiazolidine-4-carboxylic acid after occupational exposure.二硫化碳。II. 职业暴露后二硫化碳的摄取及其代谢产物2-硫代噻唑烷-4-羧酸排泄的研究。
Int Arch Occup Environ Health. 1995;67(1):5-10. doi: 10.1007/BF00383126.
5
Relation between the iodine azide test and the TTCA test for exposure to carbon disulphide.叠氮化碘试验与二硫化碳暴露的TTCA试验之间的关系。
Br J Ind Med. 1984 Aug;41(3):412-6. doi: 10.1136/oem.41.3.412.
6
Experimental human exposure to carbon disulfide. II. Urinary excretion of 2-thiothiazolidine-4-carboxylic acid (TTCA) during and after exposure.人体对二硫化碳的实验性暴露。II. 暴露期间及之后2-硫代噻唑烷-4-羧酸（TTCA）的尿排泄情况。
Int Arch Occup Environ Health. 1987;59(3):243-50. doi: 10.1007/BF00377736.
7
Accumulation of carbon disulphide metabolites.二硫化碳代谢物的积累
Int Arch Occup Environ Health. 1990;62(6):479-82. doi: 10.1007/BF00379067.