洗漱用品和化妆品被挥发性和非挥发性N-亚硝基致癌物污染。
Contamination of toiletries and cosmetic products with volatile and nonvolatile N-nitroso carcinogens.
作者信息
Spiegelhalder B, Preussmann R
出版信息
J Cancer Res Clin Oncol. 1984;108(1):160-3. doi: 10.1007/BF00390990.
Abstract
Commercially available cosmetics and toiletries were analyzed for contamination with volatile and nonvolatile N-nitrosamines. Of a total of 145 samples analyzed 50 were found to contain N-nitrosodimethylamine (max. value found 24 micrograms/kg), 26 samples were contaminated with N-nitrosomorpholine (max. value found 640 micrograms/kg), and 25 samples contained N-nitrosodiethanolamine, a non-volatile carcinogen (max. value found 1400 micrograms/kg). These results are discussed and compared with other published data on NDE1A in cosmetics, with reference to potential human exposure and to possible preventive measures.
摘要
对市售化妆品和洗漱用品进行了挥发性和非挥发性N-亚硝胺污染分析。在总共分析的145个样品中，发现50个含有N-亚硝基二甲胺（最高值为24微克/千克），26个样品被N-亚硝基吗啉污染（最高值为640微克/千克），25个样品含有非挥发性致癌物N-亚硝基二乙醇胺（最高值为1400微克/千克）。结合潜在的人体暴露情况和可能的预防措施，对这些结果进行了讨论，并与其他已发表的关于化妆品中NDE1A的相关数据进行了比较。
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