Olsen J, Sabroe S
J Epidemiol Community Health. 1984 Jun;38(2):117-21. doi: 10.1136/jech.38.2.117.
In a case-control study of all new cases of laryngeal cancer in Denmark from 1980 to 1982, 326 cases and 1134 community selected controls participated. Questionnaires were used to obtain information on education, occupation, and number of occupational exposures as well as smoking and drinking habits. High risk ratios for laryngeal cancer were found for semiskilled and unskilled workers, workers exposed to dust, out of doors workers, drivers, and people working in the cement industries and port services. The study hypothesis was that exposure to chromium or nickel increases the incidence rate of laryngeal cancer. No support for this was found concerning chromium, but exposure to nickel had a statistically significant risk ratio of 1.7.
在一项针对1980年至1982年丹麦所有喉癌新发病例的病例对照研究中,326例病例和1134名社区选定的对照参与其中。通过问卷调查获取有关教育程度、职业、职业暴露次数以及吸烟和饮酒习惯的信息。发现半熟练和非熟练工人、接触粉尘的工人、户外工作者、司机以及从事水泥行业和港口服务的人员患喉癌的风险比很高。该研究的假设是,接触铬或镍会增加喉癌的发病率。关于铬未发现对此的支持,但接触镍的风险比在统计学上具有显著意义,为1.7。