Hay E, Royds J A, Davies-Jones G A, Lewtas N A, Timperley W R, Taylor C B
J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):724-9. doi: 10.1136/jnnp.47.7.724.
This study relates the level of alpha and gamma enolase in cerebrospinal fluid sampled within 4 days of a stroke to the volume of the cerebral infarct measured on the CT image and to the clinical outcome of the patient. Twenty-eight patients were studied, two with transient ischaemic attacks and 26 with completed stroke due to infarction. The cerebrospinal fluid enolase was raised in the two patients with transient ischaemic attacks and 23 with completed stroke. There was a positive correlation between the volume of the infarct and the level of cerebrospinal fluid alpha and gamma enolase. A high cerebrospinal fluid enolase was always associated with a poor prognosis.
本研究将中风后4天内采集的脑脊液中α-烯醇化酶和γ-烯醇化酶的水平与CT图像上测量的脑梗死体积以及患者的临床结局相关联。研究了28例患者，其中2例为短暂性脑缺血发作，26例为因梗死导致的完全性中风。2例短暂性脑缺血发作患者和23例完全性中风患者的脑脊液烯醇化酶升高。梗死体积与脑脊液α-烯醇化酶和γ-烯醇化酶水平之间存在正相关。脑脊液烯醇化酶水平高总是与预后不良相关。
