霍奇金病中醋酸α-萘酯酶阳性细胞的定量研究。
A quantitative study of alpha-naphthyl acetate esterase-positive cells in Hodgkin's disease.
作者信息
Crocker J, Jones E L, Curran R C
出版信息
J Clin Pathol. 1982 Dec;35(12):1301-6. doi: 10.1136/jcp.35.12.1301.
The numbers of alpha-naphthyl acetate esterase (ANAE)-positive cells (other than T cells) have been counted in 32 specimens of Hodgkin's disease and two specimens of histiocytic lymphoma. The different Rye subtypes of Hodgkin's disease contain varying numbers of enzyme-positive cells, ranging from 1.8-16% in the lymphocyte-predominant form to 39.8-47% in lymphocyte-depleted Hodgkin's disease. The percentage of enzyme-positive cells in the mixed cellularity variety was from only 6.5 to 14.6%. In the two specimens of apparently genuine histiocytic lymphoma, the enzyme-positive cells constituted 95.2 and 97.5% respectively of all cells. Thus, the numbers of macrophages and macrophage-like cells in true histiocytic lymphoma are much greater than in Hodgkin's disease.
在32例霍奇金病标本和2例组织细胞淋巴瘤标本中，对醋酸α萘酯酶（ANAE）阳性细胞（T细胞除外）进行了计数。霍奇金病不同的Rye亚型含有数量不等的酶阳性细胞，从淋巴细胞为主型的1.8% - 16%到淋巴细胞消减型霍奇金病的39.8% - 47%。混合细胞型中酶阳性细胞的百分比仅为6.5%至14.6%。在2例明显为真性组织细胞淋巴瘤的标本中，酶阳性细胞分别占所有细胞的95.2%和97.5%。因此，真性组织细胞淋巴瘤中巨噬细胞和巨噬样细胞的数量远多于霍奇金病。
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