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非霍奇金淋巴瘤和反应性淋巴结中醋酸α-萘酯酶阳性细胞的定量研究

A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes.

作者信息

Crocker J, Jones E L, Curran R C

出版信息

J Clin Pathol. 1982 Oct;35(10):1066-8. doi: 10.1136/jcp.35.10.1066.

Abstract

The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes.

摘要

利用Reichert-Jung(Kontron)MOP-AMO3用户控制图像分析仪,对非霍奇金淋巴瘤(NHL)和反应性淋巴结中含α-萘乙酸酯酶(ANAE)的细胞(T淋巴细胞除外)数量进行了计数。检查了20例NHL标本和10个反应性淋巴结。通过固定冰冻切片中酸性α-萘乙酸酯酶(ANAE)的含量来显示细胞。结果发现,高度恶性淋巴瘤中ANAE阳性细胞的数量(10.8 - 20.5%)比低度恶性淋巴瘤(1.4 - 4.1%)多得多。反应性淋巴结中ANAE阳性细胞的数量(1.4 - 3.2%)与低度NHL淋巴结中的相似。

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