Tohgi H, Yamanouchi H, Murakami M, Kameyama M
Stroke. 1978 Jul-Aug;9(4):369-74. doi: 10.1161/01.str.9.4.369.
The relationship between the indicence of cerebral infarction and the hematocrit was studied using 432 consecutive autopsied patients with the average age of 77.1 years. The incidence of cerebral infraction was higher in patients with hematocrit values of more than 46%, (the average in younger adult subjects). The increase in the frequency of cerebral infarction with high hematocrit values was more conspicuous in patients with severe cerebral atherosclerosis than in those with slight cerebral atherosclerosis. High blood pressure per se did not influence the relationship between the hematocrit value and the incidence of cerebral infarction. With hematocrit values of more than 41%, cerebral infarction occurred more frequently in patients over 78 years of age than in the younger patients, but the difference was not significant statistically. High hematocrit values are associated with a higher risk of cerebral infarction in deep subcortical structures of the brain than for cartical infarctions. The pathogenetic and preventive implications of these results are discussed in the light of blood rheology.
对432例平均年龄为77.1岁的连续尸检患者进行研究，以探讨脑梗死发生率与血细胞比容之间的关系。血细胞比容值超过46%（年轻成人受试者的平均值）的患者脑梗死发生率更高。血细胞比容值高时，重度脑动脉粥样硬化患者脑梗死频率的增加比轻度脑动脉粥样硬化患者更明显。高血压本身并不影响血细胞比容值与脑梗死发生率之间的关系。血细胞比容值超过41%时，78岁以上患者脑梗死的发生频率高于年轻患者，但差异无统计学意义。与皮质梗死相比，高血细胞比容值与脑深部皮质下结构发生脑梗死的风险更高相关。根据血液流变学对这些结果的发病机制和预防意义进行了讨论。
