1980 - 1981年泰国恶性疟门诊治疗五种方案的评估。
An evaluation of five regimens for the outpatient therapy of falciparum malaria in Thailand 1980-81.
作者信息
Pinichpongse S, Doberstyn E B, Cullen J R, Yisunsri L, Thongsombun Y, Thimasarn K
出版信息
Bull World Health Organ. 1982;60(6):907-12.
Abstract
Five regimens for the radical treatment of falciparum malaria were compared in five geographically separate areas of Thailand. The cure rate for sulfadoxine-pyrimethamine was found to be low in the area of the Kampuchean border and in the northeastern and western parts of the country. This distribution may be related to the spread of resistant parasites through the migration of labourers. A 7-day course of quinine was found to be uniformly effective, with an overall cure rate of 90% in these primary infections with comparatively low parasitaemia.
摘要
在泰国五个地理位置分散的地区对五种根治恶性疟的治疗方案进行了比较。在柬埔寨边境地区以及泰国东北部和西部地区，发现周效磺胺-乙胺嘧啶的治愈率较低。这种分布情况可能与抗药寄生虫通过劳工迁移而传播有关。发现一个为期7天的奎宁疗程具有一致的疗效，在这些原虫血症相对较低的初次感染中，总体治愈率为90%。
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