用甲氟喹或乙胺嘧啶-磺胺多辛单剂量治疗恶性疟。
Single-dose therapy of falciparum malaria with mefloquine or pyrimethamine-sulfadoxine.
作者信息
Doberstyn E B, Phintuyothin P, Noeypatimanondh S, Teerakiartkamjorn C
出版信息
Bull World Health Organ. 1979;57(2):275-9.
Abstract
A single oral dose (1.5 g) of mefloquine hydrochloride cured all of 37 patients with falciparum malaria, and a single dose of pyrimethamine (75 mg) plus sulfadoxine (1.5 g) cured 34 of 38 patients. The rates at which parasitaemia and fever abated were similar for the two regimens but mefloquine was associated with a higher incidence of gastrointestinal side effects.
摘要
单次口服1.5克盐酸甲氟喹治愈了37例恶性疟患者，单次口服75毫克乙胺嘧啶加1.5克磺胺多辛治愈了38例患者中的34例。两种治疗方案的疟原虫血症和发热消退率相似，但甲氟喹的胃肠道副作用发生率较高。
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