阿莫地喹治疗盘尾丝虫病的临床试验。
Clinical trials of amodiaquine in onchocerciasis.
作者信息
Kale O O
出版信息
Bull World Health Organ. 1982;60(6):929-32.
Abstract
Twenty onchocerciasis patients from the rain-forest zone of Western Nigeria were treated with amodiaquine in total dosages ranging from 22 to 68 mg/kg of body weight given over 2-9 days. There was no activity against either the microfilariae or adult forms of Onchocerca volvulus. It is concluded that the drug, which was poorly tolerated by 12 patients, is ineffective against human onchocerciasis.
摘要
来自尼日利亚西部雨林地区的20名盘尾丝虫病患者接受了阿莫地喹治疗，总剂量为22至68毫克/千克体重，给药时间为2至9天。该药物对旋盘尾丝虫的微丝蚴或成虫均无作用。得出的结论是，12名患者对该药物耐受性较差，它对人类盘尾丝虫病无效。
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