Klauber A, Ottovay E
Acta Ophthalmol (Copenh). 1982 Oct;60(5):838-44. doi: 10.1111/j.1755-3768.1982.tb06748.x.
38 patients with herpes simplex keratitis were treated in double blind clinical trial. 18 patients (10 with pure epithelial and 8 with accompanying stromal affection) were treated with 3% acyclovir (ACV) eye ointment, and 20 patients (10 with pure epithelial and 10 with accompanying stromal affection) were treated with 0.5% idoxiuridine (IDU). The cure rate was 94% in the ACV group compared to 70% in the IDU group. This was significantly higher in the ACV group. Only minor adverse reactions were recorded.
38例单纯疱疹性角膜炎患者参与了双盲临床试验。18例患者（10例单纯上皮型和8例伴有基质病变）接受3%阿昔洛韦（ACV）眼膏治疗，20例患者（10例单纯上皮型和10例伴有基质病变）接受0.5%碘苷（IDU）治疗。ACV组的治愈率为94%，而IDU组为70%。ACV组的治愈率显著更高。仅记录到轻微的不良反应。
