Medvedev V I, Rodionov G A
Vopr Onkol. 1978;24(6):94-9.
The complex of agents migrating from low-dispersed soot resins PM-15 and PGM-33, injected in the stomach or applied onto the skin of mice C57Bl, showed an insignificant blastomogenic activity. Most sensitive to their effect were the tissues of organs at the site of injection (proventricular papillomas in 8.3% of cases, skin papillomas in 12.5%), in the lung (adenomas in 12.5%) and in the pancreas (fibroadenoma in 4.2%). In the negative control groups of animals no tumors of such localization were noted. The whole complex of substances migrating from resins renders the blastomogenic effect, i. e. there is a combined action with an enhancement of blastomogenic effect.
从低分散度的烟尘树脂PM - 15和PGM - 33中迁移出来的物质复合体，注入小鼠C57Bl的胃内或涂抹于其皮肤上，显示出微不足道的致瘤活性。对其作用最敏感的是注射部位器官的组织（前胃乳头状瘤占8.3%的病例，皮肤乳头状瘤占12.5%）、肺（腺瘤占12.5%）和胰腺（纤维腺瘤占4.2%）。在动物的阴性对照组中未发现此类定位的肿瘤。从树脂中迁移出来的整个物质复合体具有致瘤作用，即存在联合作用且致瘤作用增强。
