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暴发性肝炎中的甲型、乙型和非甲非乙型肝炎。

Hepatitis type A, B, and non-A non-B in fulminant hepatitis.

作者信息

Mathiesen L R, Skinoj P, Nielsen J O, Purcell R H, Wong D, Ranek L

出版信息

Gut. 1980 Jan;21(1):72-7. doi: 10.1136/gut.21.1.72.

Abstract

Serological investigations for hepatitis B surface and e antigen, antibody to hepatitis B surface, core and e antigen and antibody to hepatitis A virus were carried out in 22 patients with fulminant hepatitis admitted to Medical Department A, Rigshospitalet, Copenhagen, in 1970-77. Nine patients had hepatitis type B and four type A. One patient had evidence of both type A and B infection, whereas the remaining eight patients showed no evidence of type A or B infection. Two of these had been treated with disulfiram and a drug aetiology could not be excluded, but in six patients no known cause of fulminant hepatitis could be determined and these patients were classified as having hepatitis type non-A non-B. The survival rate was not statistically different for patients having type A, B, or non-A non-B hepatitis.

摘要

1970年至1977年期间,对哥本哈根里格霍斯医院A内科收治的22例暴发性肝炎患者进行了乙肝表面抗原和e抗原、乙肝表面抗体、核心抗体、e抗体以及甲肝病毒抗体的血清学调查。9例患者为B型肝炎,4例为A型肝炎。1例患者有A、B型感染的证据,而其余8例患者无A、B型感染的证据。其中2例曾接受双硫仑治疗,不能排除药物病因,但6例患者暴发性肝炎的已知病因无法确定,这些患者被归类为非A非B型肝炎。A、B型或非A非B型肝炎患者的生存率无统计学差异。

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Disulfiram hepatotoxicity.双硫仑肝毒性。
Br Med J. 1977 Jul 9;2(6079):94-6. doi: 10.1136/bmj.2.6079.94.

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