Bandlow G, Kühne J
Med Microbiol Immunol. 1980 Feb;168(1):55-62. doi: 10.1007/BF02121652.
Sodium thioglycollate-induced peritoneal macrophages from C3D2F1 mice were examined for their ability to produce and secrete lysozyme in vitro. Lysozyme was quantitated by use of a "lysoplate assay", in which lyophilized Micrococcus lysodeicticus suspended in agar were lysed by the enzyme. The ability to secrete lysozyme decreased in mice bearing a subcutaneous or intraperitoneal mastocytoma P-815 with progressive tumour growth.
检测了来自C3D2F1小鼠的巯基乙酸钠诱导的腹腔巨噬细胞在体外产生和分泌溶菌酶的能力。溶菌酶通过“溶菌酶平板试验”进行定量,在该试验中,悬浮在琼脂中的冻干溶壁微球菌被该酶溶解。随着皮下或腹腔肥大细胞瘤P-815肿瘤的逐渐生长,小鼠分泌溶菌酶的能力下降。