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携带肥大细胞瘤P-815的C3D2F1小鼠腹腔巨噬细胞溶菌酶产生异常。

Abnormal lysozyme production of peritoneal macrophages from mastocytoma P-815 bearing C3D2F1-mice.

作者信息

Bandlow G, Kühne J

出版信息

Med Microbiol Immunol. 1980 Feb;168(1):55-62. doi: 10.1007/BF02121652.

DOI:10.1007/BF02121652
PMID:6770238
Abstract

Sodium thioglycollate-induced peritoneal macrophages from C3D2F1 mice were examined for their ability to produce and secrete lysozyme in vitro. Lysozyme was quantitated by use of a "lysoplate assay", in which lyophilized Micrococcus lysodeicticus suspended in agar were lysed by the enzyme. The ability to secrete lysozyme decreased in mice bearing a subcutaneous or intraperitoneal mastocytoma P-815 with progressive tumour growth.

摘要

检测了来自C3D2F1小鼠的巯基乙酸钠诱导的腹腔巨噬细胞在体外产生和分泌溶菌酶的能力。溶菌酶通过“溶菌酶平板试验”进行定量,在该试验中,悬浮在琼脂中的冻干溶壁微球菌被该酶溶解。随着皮下或腹腔肥大细胞瘤P-815肿瘤的逐渐生长,小鼠分泌溶菌酶的能力下降。

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Abnormal lysozyme production of peritoneal macrophages from mastocytoma P-815 bearing C3D2F1-mice.携带肥大细胞瘤P-815的C3D2F1小鼠腹腔巨噬细胞溶菌酶产生异常。
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本文引用的文献

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Variations of the content of lysozyme in normal rats and rats bearing Jensen sarcoma following surgery.正常大鼠及荷詹森肉瘤大鼠术后溶菌酶含量的变化。
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Macrophages in syngeneic animal tumours.同基因动物肿瘤中的巨噬细胞。
Transplantation. 1972 Oct;14(4):468-73. doi: 10.1097/00007890-197210000-00011.
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Macrophage content of tumours in relation to metastatic spread and host immune reaction.肿瘤中的巨噬细胞含量与转移扩散及宿主免疫反应的关系。
Nature. 1974 Aug 23;250(5468):667-9. doi: 10.1038/250667a0.