Vir S C, Love A H
Am J Clin Nutr. 1978 Aug;31(8):1383-91. doi: 10.1093/ajcn/31.8.1383.
Nutritional status of vitamin B6 was investigated in two groups of 102 hospitalized aged. Vitamin B6 intake was estimated. Erythrocyte glutamic-pyruvic transaminase stimulation in vitro with pyridoxal phosphate and SGOT were studied as the biochemical criteria of vitamin B6 status: 18.6% of the subjects consumed less than 0.66 mg of vitamin B6 per day; 28.4% showed a percentage stimulation in vitro with pyridoxal phosphate of more than 15%. There was no significant correlation between basal erythrocyte glutamic-pyruvic transaminase activity and dietary protein, dietary vitamin B6 dietary vitamin B6/100 g of protein, SGOT, hemoglobin, mean corpuscular volume, and iron. All the biochemical parameters used for evaluating vitamin B6 status appeared higher in females, but no statistical difference between male and female groups was noted. Only SGOT levels of female subjects reflected their vitamin B6 status. A large individual variation of vitamin B6 requirement was indicated in both groups studied. Supplements with 2.5 mg of vitamin B6 to deficient subjects caused an increase in transaminase levels, though females showed a higher response. A higher recommended allowance of vitamin B6 for the aged male and female subjects was considered desirable.
对两组共102名住院老年人的维生素B6营养状况进行了调查。估算了维生素B6的摄入量。研究了磷酸吡哆醛体外刺激红细胞谷丙转氨酶及血清谷草转氨酶，以此作为维生素B6状况的生化指标：18.6%的受试者每日维生素B6摄入量不足0.66毫克；28.4%的受试者体外磷酸吡哆醛刺激率超过15%。红细胞谷丙转氨酶基础活性与膳食蛋白质、膳食维生素B6、每100克蛋白质中的膳食维生素B6、血清谷草转氨酶、血红蛋白、平均红细胞体积及铁之间无显著相关性。用于评估维生素B6状况的所有生化参数在女性中似乎更高，但男女组之间未发现统计学差异。仅女性受试者的血清谷草转氨酶水平反映了其维生素B6状况。在所研究的两组中均显示出维生素B6需求量存在较大个体差异。给缺乏维生素B6的受试者补充2.5毫克维生素B6会导致转氨酶水平升高，不过女性的反应更高。考虑到老年男性和女性受试者需要更高的维生素B6推荐摄入量。
