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Immunological blockade of endogenous thyrotropin-releasing hormone produces hypothermia in rats.

作者信息

Prasad C, Jacobs J J, Wilber J F

出版信息

Brain Res. 1980 Jul 14;193(2):580-3. doi: 10.1016/0006-8993(80)90193-6.

DOI:10.1016/0006-8993(80)90193-6
PMID:6770963
Abstract

Administration of anti-serum to thyrotropin-releasing hormone (TRH) into the lateral cerebral ventricle of rats produces a dose-dependent hypothermia. Neutralization of anti-TRH serum with excess TRH abolishes this hypothermic effect. These results suggest a thermoregulatory role for endogenous TRH in the rat central nervous system.

摘要

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