Scheiff J M, Cordier A C, Haumont S
Anat Embryol (Berl). 1978 Jun 2;153(2):115-22. doi: 10.1007/BF00343368.
At one month, the thymus weight of NMRI mice heterozygous for the Nu gene was lower than that of the wild type. However, the thymic structure was normal and no significant anomalies at the ultrastructurallevel could be found either in epithelial cells or in thymocytes. Stereologic data showed that the loss of weight was only due to a decrease of the lymphoid population, whereas the absolute number of epithelial cells was unmodified. Several hypotheses that could explain the reduced number of thymocytes were discussed.
在一个月时，Nu基因杂合的NMRI小鼠的胸腺重量低于野生型小鼠。然而，胸腺结构正常，在上皮细胞或胸腺细胞的超微结构水平均未发现明显异常。体视学数据表明，重量减轻仅归因于淋巴细胞群体的减少，而上皮细胞的绝对数量未改变。讨论了几种可以解释胸腺细胞数量减少的假说。
