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X射线对腺病毒感染细胞中病毒产生和DNA合成的影响。

Effect of X rays on virus production and DNA synthesis in adenovirus-infected cells.

作者信息

Majle T, Semkow R, Gorzkowski B

出版信息

Acta Microbiol Pol. 1977;26(1):27-33.

PMID:67751
Abstract

The effect of X rays on the process of type 10 adenovirus infection in HeLa cells was tested. CPE development and virus infections titer were lower in the irradiated cells, while CF titer remained unchanged. The rate of DNA synthesis, as measured by 3H-thymidine incorporation, was higher in the infected cells and radiosensitivity of the process was higher in the infected cells compared with uninfected controls.

摘要

测试了X射线对HeLa细胞中10型腺病毒感染过程的影响。在受照射的细胞中,细胞病变效应(CPE)的发展和病毒感染滴度较低,而补体结合(CF)滴度保持不变。通过3H-胸腺嘧啶核苷掺入法测定,感染细胞中的DNA合成速率较高,并且与未感染的对照相比,感染细胞中该过程的放射敏感性更高。

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