2型腺病毒感染的HeLa细胞中的线粒体DNA合成
Mitochondrial DNA synthesis in adenovirus type 2-infected HeLa cells.
作者信息
Fisher P B, Horwitz M S
出版信息
J Virol. 1977 May;22(2):340-5. doi: 10.1128/JVI.22.2.340-345.1977.
Abstract
Mitochondrial DNA synthesis in adenovirus type 2-infected HeLa cells was measured at various times from 0 to 24 h postinfection. Although viral infection effectively turned off host chromosomal DNA synthesis, mitochondrial DNA synthesis was not inhibited. These findings indicate a dissociation between the regulation of host and mitochondrial DNA synthesis after infection with adenovirus type 2.
摘要
在感染2型腺病毒的HeLa细胞中，于感染后0至24小时的不同时间点测量线粒体DNA合成。尽管病毒感染有效地关闭了宿主染色体DNA合成，但线粒体DNA合成并未受到抑制。这些发现表明，感染2型腺病毒后，宿主和线粒体DNA合成的调控之间存在分离。
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