[非洲伯基特淋巴瘤连续细胞系中的t(2;8)和t(8;22)易位]
[Translocations t(2;8) and t(8;22) in continuous cell lines of African Burkitt's lymphoma].
作者信息
Bernheim A, Berger R, Lenoir G
出版信息
C R Seances Acad Sci D. 1980 Sep 15;291(2):237-9.
PMID:6775833
Abstract
Chromosome studies were performed by EBV positive African Burkitt lymphoma cell lines. Variant translocations were found in 4 cases: two with t(2;8) (p12;q23 ou 24) and two with t(8;22) (q23 or 24;q11). Identical translocations were observed in EBV positive or negative non-african lymphomas or Burkitt type leukemia. These results show the uniqueness of Burkitt lymphoma leukemia and stress the importance of chromosome 8 rearrangement in this tumor.
摘要
采用EBV阳性的非洲伯基特淋巴瘤细胞系进行染色体研究。在4例中发现了变异易位：2例为t(2;8)(p12;q23或24)，2例为t(8;22)(q23或24;q11)。在EBV阳性或阴性的非非洲淋巴瘤或伯基特型白血病中观察到相同的易位。这些结果显示了伯基特淋巴瘤白血病的独特性，并强调了8号染色体重排在该肿瘤中的重要性。
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