Degen R
Schweiz Arch Neurol Neurochir Psychiatr. 1980;127(1):15-29.
The sleep EEGs of 52 children suffering from febrile seizures were recorded. Their waking EEGs were free of epileptic activity. Only a few patients fell asleep without medication, the majority received 2 mg/kg body weight of promazine hydrochloride. Epileptic activity occurred in the sleep EEG of 15 out of 52 patients (29%). Exclusively short generalized paroxysms of high amplitude, mostly irregular and partially abortive 3-4/sec spike-wave complexes and occasional 2.5/sec sharp-slow-wave complexes were recorded. Epileptic discharges were detected in the B stage in 11 patients, in the C stage in 10 patients, in the A stage in 7 patients and in the stage D in two patients. They were recorded more often in cases where more than one seizure had occurred, and where the patients were more than two years of age. Generalized spikes and waves were also seen most frequently in the case of so-called complicated febrile convulsions. Although there were differences in the cases of females, in incidences of a family history of seizures and delayed toilet training, these were not statistical significant. Likewise, a complicated pregnancy and birth as well as a delayed stato-motoric development showed no correlation. These results together with other findings justify the conclusion, that the majority of febrile convulsions should be classified amongst the primary generalized epilepsies.
记录了52例热性惊厥儿童的睡眠脑电图。他们的清醒脑电图无癫痫活动。只有少数患者未用药入睡,大多数患者接受了2mg/kg体重的盐酸异丙嗪。52例患者中有15例(29%)的睡眠脑电图出现癫痫活动。记录到的主要是高幅短程全身性阵发,大多不规则且部分为顿挫型的3 - 4次/秒棘慢波综合波,偶尔还有2.5次/秒尖慢波综合波。11例患者在B期检测到癫痫放电,10例在C期,7例在A期,2例在D期。癫痫放电在发作不止一次以及年龄超过两岁的患者中更常出现。在所谓复杂性热性惊厥病例中,全身性棘波和慢波也最常见。虽然女性病例、癫痫家族史发生率和排便训练延迟情况存在差异,但无统计学意义。同样,复杂的妊娠和分娩以及运动发育迟缓也无相关性。这些结果连同其他发现证明了这样的结论,即大多数热性惊厥应归类于原发性全身性癫痫。