通过交叉免疫电泳显示的肺炎支原体抗原
Mycoplasma pneumoniae antigens demonstrated by crossed immunoelectrophoresis.
作者信息
Schütten H J, Mogensen H H, Lind K
出版信息
Acta Pathol Microbiol Scand C. 1980 Jun;88(3):137-43. doi: 10.1111/j.1699-0463.1980.tb00086.x.
Soluble Mycoplasma pneumoniae antigens were analysed by crossed immunoelectrophoresis. At least 15 precipitation arcs were developed between the soluble antigens and rabbit anti-Mycoplasma pneumoniae hyperimmune sera. Sera from Mycoplasma pneumoniae infected patients formed precipitation arcs which were identified with those formed by a chloroform-methanol extract of Mycoplasma pneumoniae. Low concentrations of human antibodies, not detectable in a complement fixation test, were found to react with these antigens. The antigens were shown to cross-react with antigens of Mycoplasma neurolyticum. Emphasis was placed on the technical development of the crossed immunoelectrophoresis for the analysis of immune-precipitable antigens of Mycoplasma pneumoniae.
采用交叉免疫电泳法分析肺炎支原体可溶性抗原。可溶性抗原与兔抗肺炎支原体超免疫血清之间至少形成了15条沉淀弧。肺炎支原体感染患者的血清形成的沉淀弧，与肺炎支原体氯仿 - 甲醇提取物形成的沉淀弧一致。发现补体结合试验中检测不到的低浓度人抗体能与这些抗原发生反应。这些抗原显示与溶神经支原体的抗原发生交叉反应。重点介绍了交叉免疫电泳技术在分析肺炎支原体免疫沉淀性抗原方面的发展。
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