Macgregor J D, MacDonald J, Ingram E A, McDonnell M, Marshall B
Br Med J (Clin Res Ed). 1981 Feb 7;282(6262):434-6. doi: 10.1136/bmj.282.6262.434.
During 1977 and 1978 an unusual epidemic of measles occurred in Shetland, affecting 1032 (5%) of the population. All age groups were represented, and 309 cases occurred in people over 15. Geographical distribution of notified cases ranged from 1% to over one-third of the population aged under 65. All the recognised complications occurred, with a significant excess of respiratory troubles (p less than 0 . 05). Complications were much less common in female patients (p less than 0 . 05). Only about 30% of children under 5 had been vaccinated against the disease, and, based on a sample population, vaccination was found to have had a protective effect of 92%. On cost effectiveness alone, uptake of vaccination by a community as susceptible as that of Shetland should clearly be encouraged and probably given high priority.
1977年至1978年间,设得兰群岛发生了一场不同寻常的麻疹疫情,波及了1032人(占总人口的5%)。各年龄组均有病例,15岁以上人群中有309例。报告病例的地理分布范围为65岁以下人口的1%至三分之一以上。所有公认的并发症都有发生,其中呼吸系统疾病显著增多(p小于0.05)。并发症在女性患者中较少见(p小于0.05)。5岁以下儿童中只有约30%接种过该疾病疫苗,基于抽样人群,发现疫苗接种具有92%的保护效果。仅从成本效益来看,像设得兰群岛这样易感染的社区显然应鼓励接种疫苗,并可能给予高度优先考虑。