枯草芽孢杆菌中维吉尼亚霉素S抗性的定位
Mapping of virginiamycin S resistance in Bacillus subtilis.
作者信息
Ron E Z, de Bethune M P, Cocito C G
出版信息
Mol Gen Genet. 1980;180(3):639-40. doi: 10.1007/BF00268073.
PMID:6780761
Abstract
Resistance to virginiamycin S (VS, a type B synergimycin) has been mapped in Bacillus subtilis. Transduction experiments with phage PBS1 indicate that the gene for virginiamycin S resistance (VSR) is cotransduced with the markers pur A16 (20%) and cys A14 (46-49%). Transformation experiments indicate that the gene for virginiamycin S resistance maps between the markers for elongation factor G and erythromycin resistance, and is therefore located within the gene cluster of ribosomal proteins.
摘要
对维吉尼亚霉素S（VS，一种B型协同霉素）的抗性已在枯草芽孢杆菌中进行了定位。用噬菌体PBS1进行的转导实验表明，维吉尼亚霉素S抗性基因（VSR）与嘌呤A16（20%）和半胱氨酸A14（46 - 49%）标记共转导。转化实验表明，维吉尼亚霉素S抗性基因位于延伸因子G和红霉素抗性标记之间，因此位于核糖体蛋白基因簇内。
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