顺铂治疗后的溶血性贫血。
Haemolytic anaemia after cisplatin treatment.
作者信息
Levi J A, Aroney R S, Dalley D N
出版信息
Br Med J (Clin Res Ed). 1981 Jun 20;282(6281):2003-4. doi: 10.1136/bmj.282.6281.2003.
Abstract
Normochromic or normocytic anaemia is a common side effect of treatment with cisplatin. Two patients treated with cisplatin 100 mg/m2 in combination with vinblastine, bleomycin, and actinomycin D developed haemolytic anaemia. Neither patient had evidence of haemolysis before treatment, and in both cases severe haemolytic anaemia developed after several courses of cisplatin and when the cancer had regressed almost completely. The importance of haemolysis in the development of anaemia after cisplatin treatment has not been investigated fully and further studies are needed.
摘要
正色素性或正细胞性贫血是顺铂治疗常见的副作用。两名接受100mg/m²顺铂联合长春碱、博来霉素和放线菌素D治疗的患者发生了溶血性贫血。两名患者在治疗前均无溶血证据，且在两个病例中，严重溶血性贫血均在顺铂治疗几个疗程后且癌症几乎完全消退时发生。顺铂治疗后溶血在贫血发生中的重要性尚未得到充分研究，需要进一步研究。
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本文引用的文献
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