Ramsay L E, Ramsay M H, Hettiarachchi J, Davies D L, Winchester J
Br Med J. 1978 Jul 22;2(6132):244-5. doi: 10.1136/bmj.2.6132.244.
Forty-nine hypertensive patients who were overweight were randomly allocated to one of three strategies for attaining weight reduction and were followed for one year. Those referred to a dietitian lost more weight (mean 5.1 kg) than those given a diet sheet (mean 2.64 kg) or simply advised by the doctor to reduce weight (mean 2.15 kg). One-third of all the patients lost 6 kg or more. Successful weight loss was associated with a highly significant and substantial improvement in blood pressure control and with less frequent increases in antihypertensive treatment.
49名超重的高血压患者被随机分配到三种减重策略中的一种,并随访一年。转诊至营养师处的患者比收到饮食清单的患者(平均减重2.64千克)或仅由医生建议减重的患者(平均减重2.15千克)减重更多(平均减重5.1千克)。所有患者中有三分之一减重6千克或更多。成功减重与血压控制的显著且实质性改善以及降压治疗频率的降低相关。