Calne R Y, Williams R, Lindop M, Farman J V, Tolley M E, Rolles K, MacDougall B, Neuberger J, Wyke R J, Raftery A T, Duffy T J, Wight D G, White D J
Br Med J (Clin Res Ed). 1981 Jul 11;283(6284):115-8. doi: 10.1136/bmj.283.6284.115.
A total of 108 orthotopic liver transplants have been carried out in the Cambridge/King's College Hospital series. Over 13 years, changes in patient selection, immunosuppression, and surgical and anaesthetic techniques have led to a steady improvement in results. Results obtained in the last 22 patients indicated that over half survive for one year. Although at considerable risk during the operation, patients with non-malignant cirrhotic diseases who survive one year have a good long-term chance of survival
在剑桥大学/国王学院医院的系列病例中,共进行了108例原位肝移植手术。在13年多的时间里,患者选择、免疫抑制以及手术和麻醉技术的变化使得治疗效果稳步改善。最近22例患者的治疗结果表明,超过半数患者存活了一年。尽管在手术期间风险很大,但患有非恶性肝硬化疾病且存活一年的患者有良好的长期存活机会。