Osborne D H, Imrie C W, Carter D C
Br J Surg. 1981 Nov;68(11):758-61. doi: 10.1002/bjs.1800681103.
The clinical course of 47 patients with gallstone-associated acute pancreatitis who had surgery during the same admission has been reviewed. In 37 patients, when the signs and symptoms of pancreatitis settled on conservative management, biliary tract surgery was safely performed during that admission without mortality. The 10 patients whose clinical condition failed to settle prior to surgery had a complicated hospital stay and a 50 per cent mortality. A revised prognostic factor grading system has been outlined in which the age factor is removed and serum transaminase levels are considered of prognostic significance only if greater than 200 u/l within 48 h of admission. This revised system gives a more accurate assessment of the severity of individual attacks of gallstone-associated acute pancreatitis.
回顾了47例在同一住院期间接受手术治疗的胆石症相关性急性胰腺炎患者的临床病程。37例患者经保守治疗胰腺炎的体征和症状缓解后,在此次住院期间安全地进行了胆道手术,无死亡病例。10例术前病情未缓解的患者住院过程复杂,死亡率为50%。已概述了一种修订的预后因素分级系统,其中去除了年龄因素,仅当入院后48小时内血清转氨酶水平大于200 U/L时才认为其具有预后意义。这种修订后的系统能更准确地评估胆石症相关性急性胰腺炎个体发作的严重程度。