Stockwell R A, Sprinz R
J Anat. 1981 Sep;133(Pt 2):309-15.
Glycosaminoglycan content and cell density of articular cartilage have been studied quantitatively in the adult rabbit in experimental lipoarthrosis. On the fourth day after injection of non-radioactive or tritium-labelled glyceryl trioleate into the synovial cavity of the knee joint, femoral condylar cartilage shows no change in cellularity. There is a 35% loss of chondroitin sulphate from the matrix, but little change in keratansulphate. The results are not affected by the presence or absence of radioactive isotope in the lipid: possible mechanisms accounting for glycosaminoglycan loss are discussed.
在成年兔实验性脂肪性关节病中，对关节软骨的糖胺聚糖含量和细胞密度进行了定量研究。在向膝关节滑膜腔注射非放射性或氚标记的甘油三油酸酯后的第四天，股骨髁软骨的细胞数量没有变化。基质中的硫酸软骨素损失了35%，但硫酸角质素变化不大。脂质中放射性同位素的存在与否不影响结果：讨论了糖胺聚糖损失的可能机制。
