Link H, Leino E, Kekoni J
Acta Neurol Scand. 1982 Jan;65(1):76-80. doi: 10.1111/j.1600-0404.1982.tb03064.x.
CSF and serum from five patients with progressive myoclonus epilepsy taken on two occasions with about one month's interval were examined for intrathecal humoral immune response. The CSF IgG and IgA index values were normal, and no oligoclonal bands were detectable by agarose electrophoresis or polyacrylamide isoelectric focusing (IEF). Immunofixation of IEF separated IgG with four different viruses as possible antigens, and autoradiography did not reveal any intrathecal antibody production. In contradiction to previous reports, no evidence was obtained for a local humoral immune response in progressive myoclonus epilepsy.
对5例进行性肌阵挛癫痫患者在大约间隔1个月的两个时间点采集的脑脊液（CSF）和血清进行了鞘内体液免疫反应检测。脑脊液IgG和IgA指数值正常，琼脂糖电泳或聚丙烯酰胺等电聚焦（IEF）均未检测到寡克隆带。用四种不同病毒作为可能抗原对IEF分离的IgG进行免疫固定，放射自显影未显示任何鞘内抗体产生。与先前报道相反，未获得进行性肌阵挛癫痫存在局部体液免疫反应的证据。
