重型地中海贫血的生存与去铁胺治疗
Survival and desferrioxamine in thalassaemia major.
作者信息
Modell B, Letsky E A, Flynn D M, Peto R, Weatherall D J
出版信息
Br Med J (Clin Res Ed). 1982 Apr 10;284(6322):1081-4. doi: 10.1136/bmj.284.6322.1081.
Abstract
A small randomised trial and observation of all patients homozygous for beta-thalassaemia in Britain born in or before 1963 indicated that those patients who had received average weekly doses of more than 4 g of desferrioxamine over the previous few years were less likely to die in the near future than were patients of similar ages who had received less, or no, desferrioxamine.
摘要
一项针对1963年及以前在英国出生的所有β地中海贫血纯合子患者的小型随机试验和观察表明，在过去几年中每周平均接受超过4克去铁胺治疗的患者，与年龄相仿但接受较少或未接受去铁胺治疗的患者相比，近期死亡的可能性较小。
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CHELATING AGENTS IN THE DIAGNOSIS AND TREATMENT OF IRON OVERLOAD IN THALASSEMIA.螯合剂在地中海贫血铁过载诊断与治疗中的应用
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