苏氨酸可防止大肠杆菌B中吡哆醇合成的去阻遏。
Threonine prevents derepression of pyridoxine synthesis in Escherichia coli B.
作者信息
Dempsey W B
出版信息
J Bacteriol. 1982 Jun;150(3):1476-8. doi: 10.1128/jb.150.3.1476-1478.1982.
Abstract
After 40 min of pyridoxal starvation, pyridoxine phosphate oxidase-less mutants of Escherichia coli B derepressed pyridoxine biosynthesis 13-fold to a rate of 1.7 X 10(-9) mol/h per mg of cells. Threonine at 100 mg/liter prevented this derepression but did not affect the continued synthesis of pyridoxine. Neither serine nor branched-chain amino acids altered the threonine effect.
摘要
在吡哆醛饥饿40分钟后，大肠杆菌B的磷酸吡哆醛氧化酶缺失突变体将吡哆醇生物合成去抑制了13倍，达到每毫克细胞1.7×10⁻⁹摩尔/小时的速率。100毫克/升的苏氨酸可阻止这种去抑制，但不影响吡哆醇的持续合成。丝氨酸和支链氨基酸均未改变苏氨酸的作用。
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