小鼠骨髓瘤细胞中的突变事件。
Mutational events in mouse myeloma cells.
作者信息
Morrison S L, Scharff M D
出版信息
Crit Rev Immunol. 1981 Sep;3(1):1-22.
PMID:6807601
Abstract
Cultured mouse myeloma cells frequently generate variants in immunoglobulin expression and structure. In this paper the authors will review the phenotypes of the variants which have been identified and discuss the mechanisms which may be responsible for the somatic instability of the immunoglobulin genes in mouse myeloma cells.
摘要
培养的小鼠骨髓瘤细胞在免疫球蛋白表达和结构方面经常产生变异体。在本文中，作者将综述已鉴定出的变异体的表型，并讨论可能导致小鼠骨髓瘤细胞中免疫球蛋白基因体细胞不稳定性的机制。
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