Eichmann F, Stieger M, Schwarz K, Konzelmann M
Schweiz Med Wochenschr. 1982 May 15;112(20):713-8.
In a period of 15 months 601 patients (440 males, 161 females) with uncomplicated genital gonorrhea were examined bacteriologically and clinically. Diagnosis was by microscopy and culture. The sensitivity of the gonococci strains to antibiotics was tested by agar disc and the agar plate dilution culture media. 10 cases of penicillinase producing gonococci strains were found among the 601 isolates. The presence of beta-lactamase activity in all strains was confirmed by the chromogenic cephalosporin test. PPNG strains proved to be highly resistant to penicillin. These strains (PPNG) have been imported from South East Asia and West Africa. Among the isolates, only 2 cases of the South East Asian strains displayed the common tetracycline resistance. All PPNG strains were sensitive to spectinomycin and cefuroxine.
在15个月的时间里，对601例无并发症的生殖器淋病患者（440例男性，161例女性）进行了细菌学和临床检查。诊断通过显微镜检查和培养进行。通过琼脂纸片法和琼脂平板稀释培养基检测淋球菌菌株对抗生素的敏感性。在601株分离株中发现了10株产青霉素酶的淋球菌菌株。通过显色头孢菌素试验证实了所有菌株中β-内酰胺酶活性的存在。产青霉素酶淋球菌菌株对青霉素高度耐药。这些菌株（产青霉素酶淋球菌）是从东南亚和西非传入的。在分离株中，只有2例东南亚菌株表现出常见的四环素耐药性。所有产青霉素酶淋球菌菌株对壮观霉素和头孢呋辛敏感。
