抗黏液糖脂蛋白抗血清促进小鼠多形核白细胞在体外对铜绿假单胞菌的吞噬和杀伤作用。
Phagocytosis and killing of Pseudomonas aeruginosa by mouse polymorphonuclear leukocytes in vitro promoted by antiserum to the slime glycolipoprotein.
作者信息
Bishop O, Orr T, Bartell P F
出版信息
Infect Immun. 1982 Jul;37(1):378-81. doi: 10.1128/iai.37.1.378-381.1982.
Abstract
The resistance of Pseudomonas aeruginosa to phagocytosis by polymorphonuclear leukocytes was overcome by opsonization with antibody to slime glycolipoprotein or, to a lesser extent, with complement. Resistance was most effectively overcome in the presence of both. Protection against viable-cell challenge conferred by anti-glycolipoprotein serum in experimental infection is discussed briefly in the light of these findings.
摘要
通过用抗黏液糖脂蛋白抗体或程度稍低一些的补体进行调理，可克服铜绿假单胞菌对多形核白细胞吞噬作用的抗性。在二者同时存在时，抗性得到最有效的克服。根据这些发现，简要讨论了抗糖脂蛋白血清在实验性感染中对活细胞攻击所提供的保护作用。
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