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[乙磺铵与抗生素对铜绿假单胞菌的联合作用]

[Combined effect of ethonium and antibiotics on Pseudomonas aeruginosa].

作者信息

Sologub V V, Pis'ko G T, Rozhavin M A

出版信息

Antibiotiki. 1982 Jun;27(6):416-8.

PMID:6810754
Abstract

The combined effect of ethonium and 5 antibiotics belonging to different groups was studied with 30 clinical strains of P. aeruginosa. A 2--8-fold increase in the activity of kanamycin and tetracycline against some strains was observed. The MIC of carbenicillin, polymycin M and cefotaxime was lowered by 2--6 times and with respect to some strains by 16--32 times. The detergent is recommended to be used in combination with some antibiotics in treatment of infections caused by resistant strains of P. aeruginosa.

摘要

用30株铜绿假单胞菌临床菌株研究了乙磺铵与5种不同组别的抗生素的联合效应。观察到卡那霉素和四环素对某些菌株的活性增加了2至8倍。羧苄青霉素、多粘菌素M和头孢噻肟的最低抑菌浓度降低了2至6倍,对某些菌株而言降低了16至32倍。推荐在治疗由铜绿假单胞菌耐药菌株引起的感染时,将该去污剂与某些抗生素联合使用。

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