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[凝集素在恰加斯病流行病学诊断及新旧世界利什曼原虫鉴别中的价值]

[The diagnostic value of lectins for the epidemiology of Chagas' disease and the differentiation of Leishmania from the Old and New World].

作者信息

Schottelius J

出版信息

Immun Infekt. 1982 Jul;10(4):142-50.

PMID:6813249
Abstract

An interspecific differentiation between T. cruzi, T. rangeli and T. conorhini can be done with the lectin II from the marine sponge Aaptos papillata. Independently from the origin the T. cruzi strains can intraspecifically subdivided into two strain-groups from WGA-type and PNA-type. The Leishmania strains from the Old World can inter- and intraspecifically distinguished by lectins while the strains from the New World form only two groups. A comparison of the agglutination-behaviour of the Leishmania parasites shows that strains of L. m. mexicana, L. b. braziliensis, L. aethiopica and L. m. amazonensis belong to the same type. The second agglutination-type includes strains of L. t. major (Near East), L. m. amazonensis and L. m. pifanoi.

摘要

利用来自海洋海绵乳头艾普斯托海绵(Aaptos papillata)的凝集素II,可以对克氏锥虫(T. cruzi)、兰氏锥虫(T. rangeli)和康氏锥虫(T. conorhini)进行种间区分。无论克氏锥虫菌株的来源如何,其在种内可细分为WGA型和PNA型两个菌株组。旧世界的利什曼原虫菌株可以通过凝集素在种间和种内进行区分,而新世界的菌株仅形成两组。利什曼原虫寄生虫凝集行为的比较表明,墨西哥利什曼原虫(L. m. mexicana)、巴西利什曼原虫(L. b. braziliensis)、埃塞俄比亚利什曼原虫(L. aethiopica)和亚马逊利什曼原虫(L. m. amazonensis)的菌株属于同一类型。第二种凝集类型包括硕大利什曼原虫(L. t. major,近东)、亚马逊利什曼原虫和皮氏利什曼原虫(L. m. pifanoi)的菌株。

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