Erickson J D, Bjerkedal T
J Epidemiol Community Health (1978). 1978 Jun;32(2):124-30. doi: 10.1136/jech.32.2.124.
Pairs of first and second births and pairs of second and third births to the same Norwegian mothers were studied to determine the association between interpregnancy interval and birth weight, stillbirth, and neonatal death. Use of the pair approach provides one birth which could possibly have been affected by the length of the interval and one birth which could not. The association of interval and birth weight for births which precede an interval is found to be equivalent to that for births which follow an interval. The data on stillbirth are compatible with higher rates at long intervals while the data on neonatal death are consistent with higher rates at short intervals. However, we conclude that manipulation of the interval between pregnancies is unlikely to have any marked, direct, beneficial effect on outcome of pregnancy.
对挪威同一母亲的头胎和二胎、二胎和三胎进行了研究,以确定妊娠间隔与出生体重、死产及新生儿死亡之间的关联。采用配对方法可获得一次可能受间隔时间长短影响的分娩和一次不受其影响的分娩。研究发现,间隔之前分娩的间隔时间与出生体重之间的关联,等同于间隔之后分娩的这一关联。死产数据显示,间隔时间长时死产率较高,而新生儿死亡数据则表明,间隔时间短时死亡率较高。然而,我们得出的结论是,人为控制孕期间隔不太可能对妊娠结局产生任何显著、直接的有益影响。