Volná F
Zentralbl Mikrobiol. 1982;137(7):587-93.
Strain resistance of the genus Escherichia, Salmonella, and Pseudomonas to hexachlorophene is inducible. Secondary resistance of the Gram-negative microorganisms to hexachlorophene is an inherited property of these strains. There are not any explicit differences of primary sensitivity to hexachlorophene between sensitive strains and those resistant to antibiotics. The secondary resistance level of Gram-negative microorganisms to hexachlorophene is also not dependent on the natural resistance (or sensitivity) of strains to antibiotics. Hexachlorophene, in concentration of 10 micrograms/ml of conjugation mixture, causes 100% inhibition of the conjugation transfer of the resistance determinants to antibiotics from tested strains with conjugative R-plasmid. The indirect secondary resistance conjugation transfer to hexachlorophene was verified in two cases. The resistance to hexachlorophene was transferred, coupled with resistance to chloramphenicol, tetracycline, and streptomycin, from the Escherichia coli strains (No. 8) and Salmonella typhimurium (No. 4) to the recipient Escherichia coli strain K 12, SZK-Ec-329/74 (No. 2).
大肠杆菌属、沙门氏菌属和假单胞菌属对六氯酚的菌株抗性是可诱导的。革兰氏阴性微生物对六氯酚的二级抗性是这些菌株的一种遗传特性。敏感菌株和对抗生素有抗性的菌株对六氯酚的初始敏感性没有任何明显差异。革兰氏阴性微生物对六氯酚的二级抗性水平也不取决于菌株对抗生素的天然抗性（或敏感性）。浓度为10微克/毫升的结合混合物中的六氯酚会导致来自带有接合性R质粒的测试菌株的抗生素抗性决定因子的接合转移受到100%的抑制。在两个案例中证实了对六氯酚的间接二级抗性接合转移。对六氯酚的抗性与对氯霉素、四环素和链霉素的抗性一起，从大肠杆菌菌株（8号）和鼠伤寒沙门氏菌（4号）转移到受体大肠杆菌菌株K 12、SZK-Ec-329/74（2号）。
