伊朗多发性硬化症中的组织相容性抗原（HLA）。
Histocompatibility antigens (HLA) in multiple sclerosis in Iran.
作者信息
Lotfi J, Nikbin B, Derakhshan I, Aghai Z, Ala F
出版信息
J Neurol Neurosurg Psychiatry. 1978 Aug;41(8):699-701. doi: 10.1136/jnnp.41.8.699.
Abstract
Thirty-five patients (19 male and 16 female) with clinically definite multiple sclerosis and 100 healthy control subjects were studied for the A and B locus of the HLA system. A significant increase of HLA A3 and A11 of the A locus and B7 of the B locus was observed in patients with multiple sclerosis compared with controls. An increase of antigen A3 was also observed in eight cases of probable multiple sclerosis. A significant increase of both A3 and B7 was observed in patients with multiple sclerosis.
摘要
对35例临床确诊的多发性硬化症患者（19例男性和16例女性）以及100名健康对照者进行了HLA系统A和B位点的研究。与对照组相比，多发性硬化症患者中观察到A位点的HLA A3和A11以及B位点的B7显著增加。在8例可能的多发性硬化症病例中也观察到抗原A3增加。多发性硬化症患者中观察到A3和B7均显著增加。
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