Extracellularly proteolysing Aspergillus fumigatus and its interaction with specific immune serum in the serum-albumin agar. A preliminary report.

Serum-Albumin Agar with the initial pH values of 5.0 or 7.0 allows diffusion and precipitation of A. fumigatus antigens (culture filtrate) and antibodies. In the zone of extracellular proteolysis by a living culture of an atypical A. fumigatus strain, precipitin bands only against a specific immune serum were found in this medium with an initial pH of 7.0. How far under such complex substrate conditions including active extracellular proteolysis, an immune reaction can take place is open to discussion.