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未经矫正的胆道闭锁的预后:最新进展。

Prognosis of uncorrected biliary atresia: an update.

作者信息

Adelman S

出版信息

J Pediatr Surg. 1978 Aug;13(4):389-91. doi: 10.1016/s0022-3468(78)80462-x.

DOI:10.1016/s0022-3468(78)80462-x
PMID:682088
Abstract

In order to provide a baseline for comparison with the results of the Kasai hepatic portoenterostomy, follow-up information was obtained for 89 infants who underwent surgical exploration alone for biliary atresia from 1956 through 1975. Of these patients, one is apparently cured, one is alive with liver failure, three are lost to follow-up and 84 are dead. The rate of apparent cure among patients with follow-up was 1.1%. The average age at death was 12 mo, the mean 10 mo. During this same period, nine patients were operated upon for neonatal biliary obstructions other than biliary atresia, and five are apparently cured. Reported apparent cure rates after the Kasai procedure or one of its variations, while not good, still compare favorably with the cure rate of unoperated patients.

摘要

为了提供一个与葛西肝门空肠吻合术结果进行比较的基线,我们获取了1956年至1975年间仅接受手术探查治疗胆道闭锁的89例婴儿的随访信息。在这些患者中,1例明显治愈,1例存活但有肝功能衰竭,3例失访,84例死亡。随访患者中的明显治愈率为1.1%。平均死亡年龄为12个月,中位数为10个月。在同一时期,9例因非胆道闭锁的新生儿胆道梗阻接受手术,其中5例明显治愈。报道的葛西手术或其变体之一后的明显治愈率虽然不高,但仍优于未手术患者的治愈率。

相似文献

1
Prognosis of uncorrected biliary atresia: an update.未经矫正的胆道闭锁的预后:最新进展。
J Pediatr Surg. 1978 Aug;13(4):389-91. doi: 10.1016/s0022-3468(78)80462-x.
2
[Complete atresia of extrahepatic bile ducts. Surgical cure with a 12-year follow-up].
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3
Neonatal jaundice: the surgical viewpoint.新生儿黄疸:外科视角
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Identification of the jaundiced infant who is likely to recover without surgical intervention.识别可能无需手术干预即可康复的黄疸婴儿。
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Treatment of biliary atresia with special reference to hepatic porto-enterostomy and its modifications.胆道闭锁的治疗,特别提及肝门肠吻合术及其改良术。
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引用本文的文献

1
Early laparoscopic Kasai's procedure in a low weight newborn.低体重新生儿的早期腹腔镜下葛西手术
J Minim Access Surg. 2007 Apr;3(2):66-9. doi: 10.4103/0972-9941.33276.
2
Orthotopic liver transplantation for congenital biliary atresia. An 11-year, single-center experience.先天性胆道闭锁的原位肝移植。一项为期11年的单中心经验。
Ann Surg. 1996 Sep;224(3):276-84; discussion 284-7. doi: 10.1097/00000658-199609000-00004.
3
Biliary atresia, an analysis of 30 cases.胆道闭锁:30例分析
Indian J Pediatr. 1982 Mar-Apr;49(397):207-14. doi: 10.1007/BF02830752.
4
Neonatal jaundice: the surgical viewpoint.新生儿黄疸:外科视角
Can Med Assoc J. 1980 Dec 20;123(12):1218-24.
5
[New developments in pediatric surgery].[小儿外科的新进展]
Langenbecks Arch Chir. 1984;364:281-6. doi: 10.1007/BF01823215.
6
Results of surgical treatment for extrahepatic biliary atresia in United Kingdom 1980-2. Survey conducted on behalf of the British Paediatric Association Gastroenterology Group and the British Association of Paediatric Surgeons.1980 - 1982年英国肝外胆道闭锁的外科治疗结果。代表英国儿科学会胃肠病学组和英国儿科学会外科医生协会进行的调查。
Br Med J (Clin Res Ed). 1985 Feb 2;290(6465):345-7. doi: 10.1136/bmj.290.6465.345.
7
Hepatitis syndrome in infancy--an epidemiological survey with 10 year follow up.婴儿期肝炎综合征——一项为期10年随访的流行病学调查
Arch Dis Child. 1985 Jun;60(6):512-6. doi: 10.1136/adc.60.6.512.
8
Ten minute radiopharmaceutical test in biliary atresia.胆道闭锁的十分钟放射性药物检查。
Arch Dis Child. 1987 Feb;62(2):180-4. doi: 10.1136/adc.62.2.180.
9
Prognosis of extrahepatic biliary atresia.肝外胆管闭锁的预后。
Arch Dis Child. 1989 Feb;64(2):214-8. doi: 10.1136/adc.64.2.214.
10
Treatment of biliary atresia.胆道闭锁的治疗
Br Med J. 1979 Jun 30;1(6180):1745-6.