Ellingsen J E, Rølla G, Eriksen H M
J Clin Periodontol. 1982 Jul;9(4):317-22. doi: 10.1111/j.1600-051x.1982.tb02098.x.
Experiments were performed in a standardized rabbit model for examination of the potential of chlorhexidine and other denaturing agents to induce dental stain together with ferric ions. The studies supported the view that denaturation may be a major aspect of the mechanism of stain formation and that iron sulphide may be one important cause for extrinsic dental stain. Analytical microprobe analysis showed high amounts of Fe and S in the stain. The stain formation could be inhibited by SnF2, possibly by a red-ox reaction. Established stain could be removed by an oxidizing agent.
在标准化兔模型中进行了实验，以研究洗必泰和其他变性剂与铁离子一起诱导牙齿染色的可能性。这些研究支持了这样一种观点，即变性可能是污渍形成机制的一个主要方面，并且硫化铁可能是牙齿外源性染色的一个重要原因。分析微探针分析表明，污渍中含有大量的铁和硫。氟化亚锡可能通过氧化还原反应抑制污渍形成。已形成的污渍可以用氧化剂去除。
