Anderson R A, Polansky M M, Bryden N A, Patterson K Y, Veillon C, Glinsmann W H
J Nutr. 1983 Feb;113(2):276-81. doi: 10.1093/jn/113.2.276.
Daily urinary chromium (Cr) excretion of 15 healthy free-living female subjects was 0.20 +/- 0.03 microgram (mean +/- SEM) and nearly identical for 27 male subjects, 0.17 +/- 0.02 microgram. Minimum Cr absorption calculated from urinary Cr excretion was about 0.4 percent. Increasing intake fivefold by Cr supplementation led to a nearly fivefold increase in Cr excretion suggesting that the extent of absorption of supplemental inorganic chromium was similar to that from normal dietary sources. Correlations between 24-hour Cr excretion and urine volume, age, total creatinine and body weight were not found. Urinary Cr concentration of samples obtained following a morning void correlated with creatinine and Cr concentration following a glucose challenge but not with serum glucose, insulin, lipid parameters, age or body weight. Similar results were obtained for urine samples obtained from subjects during Cr supplementation. These results suggest that urinary Cr excretion does not appear to be a meaningful indicator of Cr status but is a meaningful indicator of Cr intake and that the absorption of supplemental inorganic Cr was similar to that of Cr from normal dietary sources.
15名健康的自由生活女性受试者的每日尿铬（Cr）排泄量为0.20±0.03微克（均值±标准误），27名男性受试者的该数值与之相近，为0.17±0.02微克。根据尿铬排泄量计算出的最低铬吸收率约为0.4%。通过补充铬使摄入量增加五倍，导致铬排泄量几乎增加了五倍，这表明补充的无机铬的吸收程度与正常饮食来源的铬相似。未发现24小时铬排泄量与尿量、年龄、总肌酐和体重之间存在相关性。早晨排尿后采集的样本的尿铬浓度与肌酐以及葡萄糖激发后的铬浓度相关，但与血糖、胰岛素、脂质参数、年龄或体重无关。在补充铬期间从受试者获取的尿样也得到了类似结果。这些结果表明，尿铬排泄似乎不是铬状态的有意义指标，但却是铬摄入量的有意义指标，并且补充的无机铬的吸收与正常饮食来源的铬相似。
